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FLUCONAZOLE vs MONISTAT 3

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$0.42 /mL

Type

RX
OTC

Active ingredient

FLUCONAZOLE
MICONAZOLE NITRATE

Dosage forms

Tablet
Kit

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Half-life

about 30 hours (range 20 to 50 hours)

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis
Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis

Get monistat 3higher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Fluconazole and Monistat 3?

Fluconazole contains Fluconazole, while Monistat 3 contains Miconazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.