Skip to content
ppharmaranks
Menu
CompaniesProductsDrug classesConditionsBest by conditionTreatmentsInteraction checkerFood & medicinesWhat pharmacies payPill identifierMedicines & breastfeedingChildren’s dosage chartsDo medicines expire?Crushing & splitting pillsHow long meds take to workAlternating Tylenol & ibuprofenDrug recallsSupplementsSafety & lawsuitsGuidesA–ZHow we rate

FLUCONAZOLE vs GYNE-LOTRIMIN 3

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. FLUCONAZOLE and GYNE-LOTRIMIN 3 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

fluconazolegyne-lotrimin 3

Rating

New
68/100

Pharmacy pays

$0.42 /mL
$0.21 /mL

Type

RX
RX

Active ingredient

FLUCONAZOLE
CLOTRIMAZOLE

Manufacturer

Ivax Sub Teva Pharms
Bayer Pharms

Dosage forms

Tablet
Topical, Tablet

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Half-life

about 30 hours (range 20 to 50 hours)
—

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis
Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis

Get gyne-lotrimin 3higher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Fluconazole or Gyne-Lotrimin 3?

Gyne-Lotrimin 3 costs pharmacies less to acquire — about $0.21 vs $0.42 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Fluconazole and Gyne-Lotrimin 3?

Fluconazole contains Fluconazole, while Gyne-Lotrimin 3 contains Clotrimazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.