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FENTANYL-12 vs METHADOSE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. FENTANYL-12 and METHADOSE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$9.51 /mL
$0.18 /mL

Type

RX
RX

Active ingredient

FENTANYL
METHADONE HYDROCHLORIDE

Dosage forms

Patch

Drug class

Opioid Agonist
Opioid Agonist

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Pain
Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is cheaper, Fentanyl-12 or Methadose?

Methadose costs pharmacies less to acquire — about $0.18 vs $9.51 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Fentanyl-12 and Methadose?

Fentanyl-12 contains Fentanyl, while Methadose contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.