FEMARA vs LETROZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	FEMARA	LETROZOLE
Rating	70/100	72/100
Pharmacy pays	~$4.50 /30	~$4.50 /30
Type	RX	RX
Active ingredient	LETROZOLE	LETROZOLE
Manufacturer	Novartis	Hikma
Dosage forms	Tablet	Tablet
Drug class	Aromatase Inhibitor	Aromatase Inhibitor
Boxed warning	None	None
Half-life	about 2 days (terminal elimination half-life)	about 2 days (terminal elimination half-life)
Treats	Breast Neoplasms	Breast Neoplasms

femara letrozole

Rating

70/100

72/100

Pharmacy pays

~$4.50 /30

Type

Active ingredient

LETROZOLE

Manufacturer

Novartis

Hikma

Dosage forms

Tablet

Drug class

Aromatase Inhibitor

Boxed warning

None

Half-life

about 2 days (terminal elimination half-life)

Treats

Breast Neoplasms

Frequently asked questions

Which is better-rated, Femara or Letrozole?

By our independent rating, Letrozole scores higher — 3.6 vs 3.5 out of 5 for Femara. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Femara or Letrozole?

Pharmacies pay about the same to acquire either one — roughly $4.50 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Femara and Letrozole?

Both Femara and Letrozole share the active ingredient Letrozole.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.