FELBAMATE vs FYCOMPA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. FELBAMATE and FYCOMPA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FELBAMATE	FYCOMPA
Rating	70/100	New
Pharmacy pays	~$30.62 /30	~$616.57 /30
Type	RX	RX
Active ingredient	FELBAMATE	PERAMPANEL
Manufacturer	Amneal	Catalyst Pharms
Dosage forms	Suspension, Tablet	Suspension, Tablet
Drug class	Anti-Epileptic Agent	Noncompetitive Ampa Glutamate Receptor Antagonist
Boxed warning	Boxed warning	Boxed warning
Treats	Seizures, Complex Partial Epilepsy, Lennox Gastaut Syndrome	Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

felbamate fycompa

Rating

70/100

New

Pharmacy pays

~$30.62 /30

~$616.57 /30

Type

Active ingredient

FELBAMATE

PERAMPANEL

Manufacturer

Amneal

Catalyst Pharms

Dosage forms

Suspension, Tablet

Drug class

Anti-Epileptic Agent

Noncompetitive Ampa Glutamate Receptor Antagonist

Boxed warning

Treats

Seizures, Complex Partial Epilepsy, Lennox Gastaut Syndrome

Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

Frequently asked questions

Which is cheaper, Felbamate or Fycompa?

Felbamate costs pharmacies less to acquire — about $30.62 vs $616.57 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Felbamate and Fycompa?

Felbamate contains Felbamate, while Fycompa contains Perampanel — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.