FAZACLO ODT vs ZYPREXA ZYDIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. FAZACLO ODT and ZYPREXA ZYDIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FAZACLO ODT	ZYPREXA ZYDIS
Rating	New	New
Pharmacy pays	~$30.62 /30	~$4.13 /30
Type	RX	RX
Active ingredient	CLOZAPINE	OLANZAPINE
Manufacturer	Jazz	Cheplapharm
Dosage forms	Tablet, orally disintegrating	Tablet, orally disintegrating
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	None	Boxed warning
Half-life	about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)	about 21 to 54 hours (mean around 30 hours)
Treats	Bipolar Disorder, Psychotic Disorders, Schizophrenia	Bipolar Disorder, Psychotic Disorders, Schizophrenia

fazaclo odt zyprexa zydis

Rating

New

Pharmacy pays

~$30.62 /30

~$4.13 /30

Type

Active ingredient

CLOZAPINE

OLANZAPINE

Manufacturer

Jazz

Cheplapharm

Dosage forms

Tablet, orally disintegrating

Drug class

Atypical Antipsychotic

Boxed warning

None

Boxed warning

Half-life

about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)

about 21 to 54 hours (mean around 30 hours)

Treats

Bipolar Disorder, Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is cheaper, Fazaclo ODT or Zyprexa Zydis?

Zyprexa Zydis costs pharmacies less to acquire — about $4.13 vs $30.62 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Fazaclo ODT and Zyprexa Zydis?

Fazaclo ODT contains Clozapine, while Zyprexa Zydis contains Olanzapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.