FAZACLO ODT vs INVEGA SUSTENNA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. FAZACLO ODT and INVEGA SUSTENNA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FAZACLO ODT	INVEGA SUSTENNA
Rating	New	70/100
Pharmacy pays	~$30.62 /30	—
Type	RX	RX
Active ingredient	CLOZAPINE	PALIPERIDONE PALMITATE
Manufacturer	Jazz	Janssen Pharms
Dosage forms	Tablet, orally disintegrating	Injectable
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	None	Boxed warning
Half-life	about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)	—
Treats	Bipolar Disorder, Psychotic Disorders, Schizophrenia	Bipolar Disorder, Depressive Disorder, Schizophrenia

fazaclo odt invega sustenna

Rating

New

70/100

Pharmacy pays

~$30.62 /30

—

Type

Active ingredient

CLOZAPINE

PALIPERIDONE PALMITATE

Manufacturer

Jazz

Janssen Pharms

Dosage forms

Tablet, orally disintegrating

Injectable

Drug class

Atypical Antipsychotic

Boxed warning

None

Boxed warning

Half-life

about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)

—

Treats

Bipolar Disorder, Psychotic Disorders, Schizophrenia

Bipolar Disorder, Depressive Disorder, Schizophrenia

Frequently asked questions

What is the difference between Fazaclo ODT and Invega Sustenna?

Fazaclo ODT contains Clozapine, while Invega Sustenna contains Paliperidone Palmitate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.