EXTINA vs TOLSURA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. EXTINA and TOLSURA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EXTINA	TOLSURA
Rating	72/100	72/100
Pharmacy pays	$0.26 /g	$0.85 /mL
Type	RX	RX
Active ingredient	KETOCONAZOLE	ITRACONAZOLE
Manufacturer	Rising	Mayne Pharma
Dosage forms	Spray/Inhaler, Topical	Capsule
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	Boxed warning
Half-life	—	Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.
Treats	Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

extina tolsura

Rating

72/100

Pharmacy pays

$0.26 /g

$0.85 /mL

Type

Active ingredient

KETOCONAZOLE

ITRACONAZOLE

Manufacturer

Rising

Mayne Pharma

Dosage forms

Spray/Inhaler, Topical

Capsule

Drug class

Azole Antifungal

Boxed warning

None

Boxed warning

Half-life

—

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Frequently asked questions

Which is better-rated, Extina or Tolsura?

Extina and Tolsura are tied at 3.6 out of 5 by our independent rating.

What is the difference between Extina and Tolsura?

Extina contains Ketoconazole, while Tolsura contains Itraconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.