EXONDYS 51 vs VYONDYS 53

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. EXONDYS 51 and VYONDYS 53 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EXONDYS 51	VYONDYS 53
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ETEPLIRSEN	GOLODIRSEN
Manufacturer	Sarepta Theraps Inc	Sarepta Theraps Inc
Dosage forms	Injectable	Injectable
Drug class	—	—
Boxed warning	None	None
Treats	Duchenne Muscular Dystrophy	Duchenne Muscular Dystrophy

exondys 51 vyondys 53

Rating

New

Pharmacy pays

—

Type

Active ingredient

ETEPLIRSEN

GOLODIRSEN

Manufacturer

Sarepta Theraps Inc

Dosage forms

Injectable

Drug class

—

Boxed warning

None

Treats

Duchenne Muscular Dystrophy

Frequently asked questions

What is the difference between Exondys 51 and Vyondys 53?

Exondys 51 contains Eteplirsen, while Vyondys 53 contains Golodirsen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.