EXFORGE HCT vs RETIN-A

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. EXFORGE HCT and RETIN-A are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EXFORGE HCT	RETIN-A
Rating	70/100	74/100
Pharmacy pays	~$0.33 /30	$1.05 /g
Type	RX	RX
Active ingredient	AMLODIPINE BESYLATE AND HYDROCHLOROTHIAZIDE AND VALSARTAN	TRETINOIN
Manufacturer	Novartis	Valeant Pharm Intl
Dosage forms	Tablet	Topical
Drug class	—	Retinoid
Boxed warning	Boxed warning	None
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	—
Treats	—	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

exforge hct retin-a

Rating

70/100

74/100

Pharmacy pays

~$0.33 /30

$1.05 /g

Type

Active ingredient

AMLODIPINE BESYLATE AND HYDROCHLOROTHIAZIDE AND VALSARTAN

TRETINOIN

Manufacturer

Novartis

Valeant Pharm Intl

Dosage forms

Tablet

Topical

Drug class

—

Retinoid

Boxed warning

None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

—

Treats

—

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

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Frequently asked questions

Which is better-rated, Exforge Hct or Retin-A?

By our independent rating, Retin-A scores higher — 3.7 vs 3.5 out of 5 for Exforge Hct. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Exforge Hct and Retin-A?

Exforge Hct contains Amlodipine Besylate and Hydrochlorothiazide and Valsartan, while Retin-A contains Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.