ETODOLAC vs NAPROXEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ETODOLAC and NAPROXEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ETODOLAC	NAPROXEN
Rating	New	72/100
Pharmacy pays	~$22.58 /30	$0.06 /mL
Type	RX	RX
Active ingredient	ETODOLAC	NAPROXEN
Manufacturer	Ivax Sub Teva Pharms	Hikma
Dosage forms	Capsule, Tablet, Tablet, extended release	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation)	about 12 to 17 hours
Treats	Rheumatoid Arthritis, Osteoarthritis, Pain	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

etodolac naproxen

Rating

New

72/100

Pharmacy pays

~$22.58 /30

$0.06 /mL

Type

Active ingredient

ETODOLAC

NAPROXEN

Manufacturer

Ivax Sub Teva Pharms

Hikma

Dosage forms

Capsule, Tablet, Tablet, extended release

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation)

about 12 to 17 hours

Treats

Rheumatoid Arthritis, Osteoarthritis, Pain

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Frequently asked questions

What is the difference between Etodolac and Naproxen?

Etodolac contains Etodolac, while Naproxen contains Naproxen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.