ESOMEPRAZOLE SODIUM vs PREVACID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ESOMEPRAZOLE SODIUM and PREVACID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ESOMEPRAZOLE SODIUM	PREVACID
Rating	New	New
Pharmacy pays	~$177.68 /30	~$5.10 /30
Type	RX	RX
Active ingredient	ESOMEPRAZOLE SODIUM	LANSOPRAZOLE
Manufacturer	Sun Pharm	Takeda Pharms USA
Dosage forms	Injectable, Powder	Capsule, delayed release
Drug class	Proton Pump Inhibitor	Proton Pump Inhibitor
Boxed warning	None	None
Half-life	—	about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours
Treats	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

esomeprazole sodium prevacid

Rating

New

Pharmacy pays

~$177.68 /30

~$5.10 /30

Type

Active ingredient

ESOMEPRAZOLE SODIUM

LANSOPRAZOLE

Manufacturer

Sun Pharm

Takeda Pharms USA

Dosage forms

Injectable, Powder

Capsule, delayed release

Drug class

Proton Pump Inhibitor

Boxed warning

None

Half-life

—

about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

Which is cheaper, Esomeprazole Sodium or Prevacid?

Prevacid costs pharmacies less to acquire — about $5.10 vs $177.68 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Esomeprazole Sodium and Prevacid?

Esomeprazole Sodium contains Esomeprazole Sodium, while Prevacid contains Lansoprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.