ESCITALOPRAM OXALATE vs ZOLOFT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. ESCITALOPRAM OXALATE and ZOLOFT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ESCITALOPRAM OXALATE	ZOLOFT
Rating	56/100	70/100
Pharmacy pays	$0.16 /mL	~$1.09 /30
Type	RX	RX
Active ingredient	ESCITALOPRAM OXALATE	SERTRALINE HYDROCHLORIDE
Manufacturer	Teva	Viatris
Dosage forms	Tablet	Solution, Tablet
Drug class	Serotonin Reuptake Inhibitor	Serotonin Reuptake Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	about 27 to 32 hours	about 26 hours
Treats	Major Depressive Disorder	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

escitalopram oxalate zoloft

Rating

56/100

70/100

Pharmacy pays

$0.16 /mL

~$1.09 /30

Type

Active ingredient

ESCITALOPRAM OXALATE

SERTRALINE HYDROCHLORIDE

Manufacturer

Teva

Viatris

Dosage forms

Tablet

Solution, Tablet

Drug class

Serotonin Reuptake Inhibitor

Boxed warning

Half-life

about 27 to 32 hours

about 26 hours

Treats

Major Depressive Disorder

Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

Get zolofthigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is better-rated, Escitalopram Oxalate or Zoloft?

By our independent rating, Zoloft scores higher — 3.5 vs 2.8 out of 5 for Escitalopram Oxalate. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Escitalopram Oxalate and Zoloft?

Escitalopram Oxalate contains Escitalopram Oxalate, while Zoloft contains Sertraline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.