ERLEADA vs XTANDI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. ERLEADA and XTANDI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ERLEADA	XTANDI
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	APALUTAMIDE	ENZALUTAMIDE
Manufacturer	Janssen Biotech	Astellas
Dosage forms	Tablet	Tablet, Capsule
Drug class	—	Androgen Receptor Inhibitor
Boxed warning	None	None
Treats	Prostatic Neoplasms	Prostatic Neoplasms

erleada xtandi

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

APALUTAMIDE

ENZALUTAMIDE

Manufacturer

Janssen Biotech

Astellas

Dosage forms

Tablet

Tablet, Capsule

Drug class

—

Androgen Receptor Inhibitor

Boxed warning

None

Treats

Prostatic Neoplasms

Frequently asked questions

What is the difference between Erleada and Xtandi?

Erleada contains Apalutamide, while Xtandi contains Enzalutamide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.