EQUETRO vs SERZONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. EQUETRO and SERZONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EQUETRO	SERZONE
Rating	72/100	72/100
Pharmacy pays	~$7.33 /30	~$39.92 /30
Type	RX	RX
Active ingredient	CARBAMAZEPINE	NEFAZODONE HYDROCHLORIDE
Manufacturer	Validus Pharms	Bristol Myers Squibb
Dosage forms	Capsule, extended release	Tablet
Drug class	Mood Stabilizer	—
Boxed warning	Boxed warning	None
Half-life	about 12 to 17 hours once you have been taking it regularly (25 to 65 hours after the very first dose)	—
Treats	Bipolar Disorder, Tonic-Clonic Epilepsy, Psychotic Disorders	Depressive Disorder, Post-Traumatic Stress Disorders

equetro serzone

Rating

72/100

Pharmacy pays

~$7.33 /30

~$39.92 /30

Type

Active ingredient

CARBAMAZEPINE

NEFAZODONE HYDROCHLORIDE

Manufacturer

Validus Pharms

Bristol Myers Squibb

Dosage forms

Capsule, extended release

Tablet

Drug class

Mood Stabilizer

—

Boxed warning

None

Half-life

about 12 to 17 hours once you have been taking it regularly (25 to 65 hours after the very first dose)

—

Treats

Bipolar Disorder, Tonic-Clonic Epilepsy, Psychotic Disorders

Depressive Disorder, Post-Traumatic Stress Disorders

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Frequently asked questions

Which is better-rated, Equetro or Serzone?

Equetro and Serzone are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Equetro or Serzone?

Equetro costs pharmacies less to acquire — about $7.33 vs $39.92 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Equetro and Serzone?

Equetro contains Carbamazepine, while Serzone contains Nefazodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.