EQUETRO vs FYCOMPA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. EQUETRO and FYCOMPA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EQUETRO	FYCOMPA
Rating	72/100	New
Pharmacy pays	~$7.33 /30	~$573.73 /30
Type	RX	RX
Active ingredient	CARBAMAZEPINE	PERAMPANEL
Manufacturer	Validus Pharms	Catalyst Pharms
Dosage forms	Capsule, extended release	Suspension, Tablet
Drug class	Mood Stabilizer	Noncompetitive Ampa Glutamate Receptor Antagonist
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12 to 17 hours once you have been taking it regularly (25 to 65 hours after the very first dose)	—
Treats	Bipolar Disorder, Tonic-Clonic Epilepsy, Psychotic Disorders	Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

equetro fycompa

Rating

72/100

New

Pharmacy pays

~$7.33 /30

~$573.73 /30

Type

Active ingredient

CARBAMAZEPINE

PERAMPANEL

Manufacturer

Validus Pharms

Catalyst Pharms

Dosage forms

Capsule, extended release

Suspension, Tablet

Drug class

Mood Stabilizer

Noncompetitive Ampa Glutamate Receptor Antagonist

Boxed warning

Half-life

about 12 to 17 hours once you have been taking it regularly (25 to 65 hours after the very first dose)

—

Treats

Bipolar Disorder, Tonic-Clonic Epilepsy, Psychotic Disorders

Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

Frequently asked questions

Which is cheaper, Equetro or Fycompa?

Equetro costs pharmacies less to acquire — about $7.33 vs $573.73 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Equetro and Fycompa?

Equetro contains Carbamazepine, while Fycompa contains Perampanel — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.