EPRONTIA vs FYCOMPA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. EPRONTIA and FYCOMPA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EPRONTIA	FYCOMPA
Rating	72/100	New
Pharmacy pays	~$3.21 /30	~$573.73 /30
Type	RX	RX
Active ingredient	TOPIRAMATE	PERAMPANEL
Manufacturer	Azurity	Catalyst Pharms
Dosage forms	Solution	Suspension, Tablet
Drug class	—	Noncompetitive Ampa Glutamate Receptor Antagonist
Boxed warning	None	Boxed warning
Half-life	about 21 hours	—
Treats	Bipolar Disorder, Partial Epilepsies, Tonic-Clonic Epilepsy	Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

eprontia fycompa

Rating

72/100

New

Pharmacy pays

~$3.21 /30

~$573.73 /30

Type

Active ingredient

TOPIRAMATE

PERAMPANEL

Manufacturer

Azurity

Catalyst Pharms

Dosage forms

Solution

Suspension, Tablet

Drug class

—

Noncompetitive Ampa Glutamate Receptor Antagonist

Boxed warning

None

Boxed warning

Half-life

about 21 hours

—

Treats

Bipolar Disorder, Partial Epilepsies, Tonic-Clonic Epilepsy

Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

Frequently asked questions

Which is cheaper, Eprontia or Fycompa?

Eprontia costs pharmacies less to acquire — about $3.21 vs $573.73 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Eprontia and Fycompa?

Eprontia contains Topiramate, while Fycompa contains Perampanel — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.