EPIPEN E Z PEN vs SYMJEPI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Attribute	EPIPEN E Z PEN	SYMJEPI
Rating	66/100	70/100
Pharmacy pays	~$3898.29 /30	~$3898.29 /30
Type	RX	RX
Active ingredient	EPINEPHRINE	EPINEPHRINE
Manufacturer	Viatris	Adamis Pharms Corp
Dosage forms	Injectable	Solution
Drug class	Catecholamine	Catecholamine
Boxed warning	None	None
Treats	Airway Obstruction, Anaphylaxis, Bradycardia	Airway Obstruction, Anaphylaxis, Bradycardia

epipen e z pen symjepi

Rating

66/100

70/100

Pharmacy pays

~$3898.29 /30

Type

Active ingredient

EPINEPHRINE

Manufacturer

Viatris

Adamis Pharms Corp

Dosage forms

Injectable

Solution

Drug class

Catecholamine

Boxed warning

None

Treats

Airway Obstruction, Anaphylaxis, Bradycardia

Frequently asked questions

Which is better-rated, Epipen E Z Pen or Symjepi?

By our independent rating, Symjepi scores higher — 3.5 vs 3.3 out of 5 for Epipen E Z Pen. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Epipen E Z Pen or Symjepi?

Pharmacies pay about the same to acquire either one — roughly $3898.29 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Epipen E Z Pen and Symjepi?

Both Epipen E Z Pen and Symjepi share the active ingredient Epinephrine.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.