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EPIPEN E Z PEN vs NEFFY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

66/100
New

Pharmacy pays

~$3898.29 /30
~$3898.29 /30

Type

RX
RX

Active ingredient

EPINEPHRINE
EPINEPHRINE

Dosage forms

Injectable
Spray/Inhaler

Drug class

Catecholamine
Catecholamine

Boxed warning

None
None

Treats

Airway Obstruction, Anaphylaxis, Bradycardia
Airway Obstruction, Anaphylaxis, Bradycardia

Frequently asked questions

Which is cheaper, Epipen E Z Pen or Neffy?

Pharmacies pay about the same to acquire either one — roughly $3898.29 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Epipen E Z Pen and Neffy?

Both Epipen E Z Pen and Neffy share the active ingredient Epinephrine.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.