ENVARSUS XR vs PROTOPIC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ENVARSUS XR	PROTOPIC
Rating	New	New
Pharmacy pays	$0.65 /g	$0.65 /g
Type	RX	RX
Active ingredient	TACROLIMUS	TACROLIMUS
Manufacturer	Veloxis Pharms Inc	Leo Pharma As
Dosage forms	Tablet, extended release	Topical
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	Boxed warning	None
Treats	Atopic Dermatitis, Graft Vs Host Disease	Atopic Dermatitis, Graft Vs Host Disease

envarsus xr protopic

Rating

New

Pharmacy pays

$0.65 /g

Type

Active ingredient

TACROLIMUS

Manufacturer

Veloxis Pharms Inc

Leo Pharma As

Dosage forms

Tablet, extended release

Topical

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Treats

Atopic Dermatitis, Graft Vs Host Disease

Frequently asked questions

Which is cheaper, Envarsus XR or Protopic?

Pharmacies pay about the same to acquire either one — roughly $0.65 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Envarsus XR and Protopic?

Both Envarsus XR and Protopic share the active ingredient Tacrolimus.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.