ENVARSUS XR vs LUPKYNIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ENVARSUS XR and LUPKYNIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ENVARSUS XR	LUPKYNIS
Rating	New	New
Pharmacy pays	$0.65 /g	—
Type	RX	RX
Active ingredient	TACROLIMUS	VOCLOSPORIN
Manufacturer	Veloxis Pharms Inc	Aurinia
Dosage forms	Tablet, extended release	Capsule
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	Boxed warning	None
Treats	Atopic Dermatitis, Graft Vs Host Disease	Lupus Nephritis

envarsus xr lupkynis

Rating

New

Pharmacy pays

$0.65 /g

—

Type

Active ingredient

TACROLIMUS

VOCLOSPORIN

Manufacturer

Veloxis Pharms Inc

Aurinia

Dosage forms

Tablet, extended release

Capsule

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Treats

Atopic Dermatitis, Graft Vs Host Disease

Lupus Nephritis

Frequently asked questions

What is the difference between Envarsus XR and Lupkynis?

Envarsus XR contains Tacrolimus, while Lupkynis contains Voclosporin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.