ENVARSUS XR vs GENGRAF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. ENVARSUS XR and GENGRAF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ENVARSUS XR	GENGRAF
Rating	New	72/100
Pharmacy pays	$0.65 /g	~$52.85 /30
Type	RX	RX
Active ingredient	TACROLIMUS	CYCLOSPORINE
Manufacturer	Veloxis Pharms Inc	Abbvie
Dosage forms	Tablet, extended release	Capsule
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 8.4 hours (range 5 to 18 hours)
Treats	Atopic Dermatitis, Graft Vs Host Disease	Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

envarsus xr gengraf

Rating

New

72/100

Pharmacy pays

$0.65 /g

~$52.85 /30

Type

Active ingredient

TACROLIMUS

CYCLOSPORINE

Manufacturer

Veloxis Pharms Inc

Abbvie

Dosage forms

Tablet, extended release

Capsule

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

Half-life

—

about 8.4 hours (range 5 to 18 hours)

Treats

Atopic Dermatitis, Graft Vs Host Disease

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Frequently asked questions

What is the difference between Envarsus XR and Gengraf?

Envarsus XR contains Tacrolimus, while Gengraf contains Cyclosporine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.