ENBREL vs HUMIRA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ENBREL and HUMIRA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ENBREL	HUMIRA
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ETANERCEPT	ADALIMUMAB
Manufacturer	Immunex	Abbvie
Dosage forms	Solution	Kit
Drug class	Tumor Necrosis Factor Blocker	Tumor Necrosis Factor Blocker
Boxed warning	Boxed warning	Boxed warning
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Ankylosing Spondylitis	Juvenile Arthritis, Rheumatoid Arthritis, Ulcerative Colitis

enbrel humira

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

ETANERCEPT

ADALIMUMAB

Manufacturer

Immunex

Abbvie

Dosage forms

Solution

Kit

Drug class

Tumor Necrosis Factor Blocker

Boxed warning

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Ankylosing Spondylitis

Juvenile Arthritis, Rheumatoid Arthritis, Ulcerative Colitis

Frequently asked questions

What is the difference between Enbrel and Humira?

Enbrel contains Etanercept, while Humira contains Adalimumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.