EMSAM vs ZELAPAR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. EMSAM and ZELAPAR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EMSAM	ZELAPAR
Rating	New	New
Pharmacy pays	~$19.56 /30	~$19.56 /30
Type	RX	RX
Active ingredient	SELEGILINE	SELEGILINE HYDROCHLORIDE
Manufacturer	Somerset	Bausch
Dosage forms	Patch	Tablet, orally disintegrating
Drug class	Monoamine Oxidase Inhibitor	Monoamine Oxidase Inhibitor
Boxed warning	None	None
Treats	Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder	Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

emsam zelapar

Rating

New

Pharmacy pays

~$19.56 /30

Type

Active ingredient

SELEGILINE

SELEGILINE HYDROCHLORIDE

Manufacturer

Somerset

Bausch

Dosage forms

Patch

Tablet, orally disintegrating

Drug class

Monoamine Oxidase Inhibitor

Boxed warning

None

Treats

Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

Get emsamhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Emsam or Zelapar?

Pharmacies pay about the same to acquire either one — roughly $19.56 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Emsam and Zelapar?

Emsam contains Selegiline, while Zelapar contains Selegiline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.