EMPAVELI vs SOLIRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. EMPAVELI and SOLIRIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	EMPAVELI	SOLIRIS
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PEGCETACOPLAN	ECULIZUMAB
Manufacturer	Apellis Pharms	Alexion Pharm
Dosage forms	Injectable	Injectable
Drug class	Complement Inhibitor	Complement Inhibitor
Boxed warning	Boxed warning	Boxed warning
Treats	Paroxysmal Hemoglobinuria	Paroxysmal Hemoglobinuria, Myasthenia Gravis, Atypical Hemolytic Uremic Syndrome

empaveli soliris

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

PEGCETACOPLAN

ECULIZUMAB

Manufacturer

Apellis Pharms

Alexion Pharm

Dosage forms

Injectable

Drug class

Complement Inhibitor

Boxed warning

Treats

Paroxysmal Hemoglobinuria

Paroxysmal Hemoglobinuria, Myasthenia Gravis, Atypical Hemolytic Uremic Syndrome

Frequently asked questions

What is the difference between Empaveli and Soliris?

Empaveli contains Pegcetacoplan, while Soliris contains Eculizumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.