ELYXYB vs PIROXICAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. ELYXYB and PIROXICAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ELYXYB	PIROXICAM
Rating	New	72/100
Pharmacy pays	~$2.51 /30	~$5.35 /30
Type	RX	RX
Active ingredient	CELECOXIB	PIROXICAM
Manufacturer	Scilex Pharms	Unichem
Dosage forms	Liquid	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 11 hours	—
Treats	Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis	Rheumatoid Arthritis, Inflammation, Osteoarthritis

elyxyb piroxicam

Rating

New

72/100

Pharmacy pays

~$2.51 /30

~$5.35 /30

Type

Active ingredient

CELECOXIB

PIROXICAM

Manufacturer

Scilex Pharms

Unichem

Dosage forms

Liquid

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 11 hours

—

Treats

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

Which is cheaper, Elyxyb or Piroxicam?

Elyxyb costs pharmacies less to acquire — about $2.51 vs $5.35 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Elyxyb and Piroxicam?

Elyxyb contains Celecoxib, while Piroxicam contains Piroxicam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.