ELSPAR vs OPDIVO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. ELSPAR and OPDIVO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ELSPAR	OPDIVO
Rating	72/100	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ASPARAGINASE	NIVOLUMAB
Manufacturer	Merck	Bristol Myers Squibb
Dosage forms	Injectable	Injectable
Drug class	—	Programmed Death Receptor-1 Blocking Antibody
Boxed warning	None	None
Treats	Cholelithiasis, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma	Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

elspar opdivo

Rating

72/100

Pharmacy pays

—

Type

Active ingredient

ASPARAGINASE

NIVOLUMAB

Manufacturer

Merck

Bristol Myers Squibb

Dosage forms

Injectable

Drug class

—

Programmed Death Receptor-1 Blocking Antibody

Boxed warning

None

Treats

Cholelithiasis, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

Frequently asked questions

Which is better-rated, Elspar or Opdivo?

Elspar and Opdivo are tied at 3.6 out of 5 by our independent rating.

What is the difference between Elspar and Opdivo?

Elspar contains Asparaginase, while Opdivo contains Nivolumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.