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EC-NAPROSYN vs JUNIOR STRENGTH ADVIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

New
72/100

Pharmacy pays

$0.06 /mL
$0.04 /mL

Type

RX
OTC

Active ingredient

NAPROXEN
IBUPROFEN

Dosage forms

Tablet, delayed release
Tablet, chewable, Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 12 to 17 hours
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Get junior strength advilhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Ec-Naprosyn or Junior Strength Advil?

Junior Strength Advil costs pharmacies less to acquire — about $0.04 vs $0.06 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Ec-Naprosyn and Junior Strength Advil?

Ec-Naprosyn contains Naproxen, while Junior Strength Advil contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.