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DYNACIRC CR vs GUANFACINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DYNACIRC CR and GUANFACINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

~$49.91 /30
~$5.26 /30

Type

RX
RX

Active ingredient

ISRADIPINE
GUANFACINE HYDROCHLORIDE

Dosage forms

Tablet, extended release
Tablet

Drug class

Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Treats

Variant Angina Pectoris, Hypertension
Attention Deficit Disorder with Hyperactivity, Hypertension

Get guanfacine hydrochloridehigher-rated option

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Frequently asked questions

Which is better-rated, Dynacirc CR or Guanfacine Hydrochloride?

By our independent rating, Guanfacine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Dynacirc CR. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dynacirc CR or Guanfacine Hydrochloride?

Guanfacine Hydrochloride costs pharmacies less to acquire — about $5.26 vs $49.91 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dynacirc CR and Guanfacine Hydrochloride?

Dynacirc CR contains Isradipine, while Guanfacine Hydrochloride contains Guanfacine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.