DURLAZA vs RUFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DURLAZA and RUFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DURLAZA	RUFEN
Rating	New	70/100
Pharmacy pays	~$0.78 /30	$0.04 /mL
Type	RX	RX
Active ingredient	ASPIRIN	IBUPROFEN
Manufacturer	Hesp	Basf
Dosage forms	Capsule, extended release	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 20 minutes (the label also states 0.33 hours) for aspirin itself	about 1.8 to 2.0 hours
Treats	Rheumatoid Arthritis, Fever, Gout	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

durlaza rufen

Rating

New

70/100

Pharmacy pays

~$0.78 /30

$0.04 /mL

Type

Active ingredient

ASPIRIN

IBUPROFEN

Manufacturer

Hesp

Basf

Dosage forms

Capsule, extended release

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself

about 1.8 to 2.0 hours

Treats

Rheumatoid Arthritis, Fever, Gout

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Frequently asked questions

What is the difference between Durlaza and Rufen?

Durlaza contains Aspirin, while Rufen contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.