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DURAMORPH PF vs SUBLIMAZE PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. DURAMORPH PF and SUBLIMAZE PRESERVATIVE FREE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

$2.61 /mL
$9.51 /mL

Type

RX
RX

Active ingredient

MORPHINE SULFATE
FENTANYL CITRATE

Manufacturer

Dosage forms

Injectable, Solution
Injectable

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 2 hours

Treats

Dyspnea, Intractable Pain
Pain

Frequently asked questions

Which is better-rated, Duramorph Pf or Sublimaze Preservative Free?

By our independent rating, Sublimaze Preservative Free scores higher — 3.6 vs 3.5 out of 5 for Duramorph Pf. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Duramorph Pf or Sublimaze Preservative Free?

Duramorph Pf costs pharmacies less to acquire — about $2.61 vs $9.51 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Duramorph Pf and Sublimaze Preservative Free?

Duramorph Pf contains Morphine Sulfate, while Sublimaze Preservative Free contains Fentanyl Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.