Skip to content
ppharmaranks
Menu

DURAGESIC-12 vs WESTADONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DURAGESIC-12 and WESTADONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
68/100

Pharmacy pays

$9.51 /mL
$0.18 /mL

Type

RX
RX

Active ingredient

FENTANYL
METHADONE HYDROCHLORIDE

Dosage forms

Film, extended release
Tablet, effervescent

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Pain
Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is better-rated, Duragesic-12 or Westadone?

By our independent rating, Duragesic-12 scores higher — 3.5 vs 3.4 out of 5 for Westadone. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Duragesic-12 or Westadone?

Westadone costs pharmacies less to acquire — about $0.18 vs $9.51 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Duragesic-12 and Westadone?

Duragesic-12 contains Fentanyl, while Westadone contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.