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DURAGESIC-12 vs SUFENTA PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. DURAGESIC-12 and SUFENTA PRESERVATIVE FREE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

duragesic-12sufenta preservative free

Rating

70/100
72/100

Pharmacy pays

$9.51 /mL
—

Type

RX
RX

Active ingredient

FENTANYL
SUFENTANIL CITRATE

Manufacturer

Janssen Pharms
Rising

Dosage forms

Film, extended release
Injectable

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Treats

Pain
Pain

Frequently asked questions

Which is better-rated, Duragesic-12 or Sufenta Preservative Free?

By our independent rating, Sufenta Preservative Free scores higher — 3.6 vs 3.5 out of 5 for Duragesic-12. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Duragesic-12 and Sufenta Preservative Free?

Duragesic-12 contains Fentanyl, while Sufenta Preservative Free contains Sufentanil Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.