Skip to content
ppharmaranks
Menu
CompaniesProductsDrug classesConditionsBest by conditionTreatmentsInteraction checkerFood & medicinesWhat pharmacies payPill identifierMedicines & breastfeedingChildren’s dosage chartsDo medicines expire?Crushing & splitting pillsHow long meds take to workAlternating Tylenol & ibuprofenDrug recallsSupplementsSafety & lawsuitsGuidesA–ZHow we rate

DURAGESIC-12 vs NUMORPHAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DURAGESIC-12 and NUMORPHAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

duragesic-12numorphan

Rating

70/100
72/100

Pharmacy pays

$9.51 /mL
~$36.74 /30

Type

RX
RX

Active ingredient

FENTANYL
OXYMORPHONE HYDROCHLORIDE

Manufacturer

Janssen Pharms
Endo Pharms

Dosage forms

Film, extended release
Suppository

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Treats

Pain
Pain

Frequently asked questions

Which is better-rated, Duragesic-12 or Numorphan?

By our independent rating, Numorphan scores higher — 3.6 vs 3.5 out of 5 for Duragesic-12. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Duragesic-12 and Numorphan?

Duragesic-12 contains Fentanyl, while Numorphan contains Oxymorphone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.