DURACLON vs ONYDA XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	DURACLON	ONYDA XR
Rating	68/100	72/100
Pharmacy pays	~$1.05 /30	~$1.05 /30
Type	RX	RX
Active ingredient	CLONIDINE HYDROCHLORIDE	CLONIDINE HYDROCHLORIDE
Manufacturer	Mylan Institutional	Tris Pharma Inc
Dosage forms	Injectable	Suspension, extended release
Drug class	Central Alpha-2 Adrenergic Agonist	Central Alpha-2 Adrenergic Agonist
Boxed warning	Boxed warning	None
Half-life	about 12 to 16 hours	about 12 to 16 hours
Treats	Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea	Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

duraclon onyda xr

Rating

68/100

72/100

Pharmacy pays

~$1.05 /30

Type

Active ingredient

CLONIDINE HYDROCHLORIDE

Manufacturer

Mylan Institutional

Tris Pharma Inc

Dosage forms

Injectable

Suspension, extended release

Drug class

Central Alpha-2 Adrenergic Agonist

Boxed warning

None

Half-life

about 12 to 16 hours

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

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Frequently asked questions

Which is better-rated, Duraclon or Onyda XR?

By our independent rating, Onyda XR scores higher — 3.6 vs 3.4 out of 5 for Duraclon. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Duraclon or Onyda XR?

Pharmacies pay about the same to acquire either one — roughly $1.05 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Duraclon and Onyda XR?

Both Duraclon and Onyda XR share the active ingredient Clonidine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.