DUOPA vs SINEMET
Independent side-by-side comparison.
Rating
70/100
70/100
Pharmacy pays
~$20.52 /30
~$20.52 /30
Type
RX
RX
Active ingredient
CARBIDOPA AND LEVODOPA
CARBIDOPA AND LEVODOPA
Dosage forms
Suspension
Tablet
Drug class
—
—
Boxed warning
None
None
Half-life
about 50 minutes (extended to about 1.5 hours when taken with carbidopa)
about 50 minutes (extended to about 1.5 hours when taken with carbidopa)
Frequently asked questions
Which is better-rated, Duopa or Sinemet?
Duopa and Sinemet are tied at 3.5 out of 5 by our independent rating.
Which is cheaper, Duopa or Sinemet?
Pharmacies pay about the same to acquire either one — roughly $20.52 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.
What is the difference between Duopa and Sinemet?
Both Duopa and Sinemet share the active ingredient Carbidopa and Levodopa.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.