DTIC-DOME vs HEPZATO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. DTIC-DOME and HEPZATO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DTIC-DOME	HEPZATO
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DACARBAZINE	MELPHALAN HYDROCHLORIDE
Manufacturer	Bayer Hlthcare	Delcath Systems Inc
Dosage forms	Injectable	Kit
Drug class	Alkylating Drug	Alkylating Drug
Boxed warning	None	Boxed warning
Treats	Fibrosarcoma, Hodgkin Disease, Melanoma	Breast Neoplasms, Multiple Myeloma, Neuroblastoma

dtic-dome hepzato

Rating

New

Pharmacy pays

—

Type

Active ingredient

DACARBAZINE

MELPHALAN HYDROCHLORIDE

Manufacturer

Bayer Hlthcare

Delcath Systems Inc

Dosage forms

Injectable

Kit

Drug class

Alkylating Drug

Boxed warning

None

Boxed warning

Treats

Fibrosarcoma, Hodgkin Disease, Melanoma

Breast Neoplasms, Multiple Myeloma, Neuroblastoma

Frequently asked questions

What is the difference between Dtic-Dome and Hepzato?

Dtic-Dome contains Dacarbazine, while Hepzato contains Melphalan Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.