DSUVIA vs ULTRAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DSUVIA and ULTRAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DSUVIA	ULTRAM
Rating	New	70/100
Pharmacy pays	—	~$0.72 /30
Type	RX	RX
Active ingredient	SUFENTANIL CITRATE	TRAMADOL HYDROCHLORIDE
Manufacturer	Vertical Pharms	Janssen Pharms
Dosage forms	Tablet	Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	—	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
Treats	Pain	Pain

dsuvia ultram

Rating

New

70/100

Pharmacy pays

—

~$0.72 /30

Type

Active ingredient

SUFENTANIL CITRATE

TRAMADOL HYDROCHLORIDE

Manufacturer

Vertical Pharms

Janssen Pharms

Dosage forms

Tablet

Drug class

Opioid Agonist

Boxed warning

None

Half-life

—

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Pain

Frequently asked questions

What is the difference between Dsuvia and Ultram?

Dsuvia contains Sufentanil Citrate, while Ultram contains Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.