DSUVIA vs METHADONE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DSUVIA and METHADONE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DSUVIA	METHADONE HYDROCHLORIDE
Rating	New	72/100
Pharmacy pays	—	$0.18 /mL
Type	RX	RX
Active ingredient	SUFENTANIL CITRATE	METHADONE HYDROCHLORIDE
Manufacturer	Vertical Pharms	Hikma
Dosage forms	Tablet	Injectable, Solution, Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	Boxed warning
Half-life	—	about 8 to 59 hours (terminal/elimination half-life; a very wide range)
Treats	Pain	Opioid-Related Disorders, Intractable Pain

dsuvia methadone hydrochloride

Rating

New

72/100

Pharmacy pays

—

$0.18 /mL

Type

Active ingredient

SUFENTANIL CITRATE

METHADONE HYDROCHLORIDE

Manufacturer

Vertical Pharms

Hikma

Dosage forms

Tablet

Injectable, Solution, Tablet

Drug class

Opioid Agonist

Boxed warning

None

Boxed warning

Half-life

—

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Pain

Opioid-Related Disorders, Intractable Pain

Frequently asked questions

What is the difference between Dsuvia and Methadone Hydrochloride?

Dsuvia contains Sufentanil Citrate, while Methadone Hydrochloride contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.