DRIZALMA SPRINKLE vs SAVELLA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DRIZALMA SPRINKLE and SAVELLA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DRIZALMA SPRINKLE	SAVELLA
Rating	New	72/100
Pharmacy pays	~$3.41 /30	~$97.10 /30
Type	RX	RX
Active ingredient	DULOXETINE HYDROCHLORIDE	MILNACIPRAN HYDROCHLORIDE
Manufacturer	Sun Pharm	Abbvie
Dosage forms	Capsule, delayed release	Kit, Tablet
Drug class	Serotonin and Norepinephrine Reuptake Inhibitor	Serotonin and Norepinephrine Reuptake Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12 hours (typically 8 to 17 hours)	—
Treats	Anxiety Disorders, Major Depressive Disorder, Diabetic Neuropathies	Major Depressive Disorder

drizalma sprinkle savella

Rating

New

72/100

Pharmacy pays

~$3.41 /30

~$97.10 /30

Type

Active ingredient

DULOXETINE HYDROCHLORIDE

MILNACIPRAN HYDROCHLORIDE

Manufacturer

Sun Pharm

Abbvie

Dosage forms

Capsule, delayed release

Kit, Tablet

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor

Boxed warning

Half-life

about 12 hours (typically 8 to 17 hours)

—

Treats

Anxiety Disorders, Major Depressive Disorder, Diabetic Neuropathies

Major Depressive Disorder

Frequently asked questions

Which is cheaper, Drizalma Sprinkle or Savella?

Drizalma Sprinkle costs pharmacies less to acquire — about $3.41 vs $97.10 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Drizalma Sprinkle and Savella?

Drizalma Sprinkle contains Duloxetine Hydrochloride, while Savella contains Milnacipran Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.