DOXYCHEL HYCLATE vs XYROSA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. DOXYCHEL HYCLATE and XYROSA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DOXYCHEL HYCLATE	XYROSA
Rating	New	New
Pharmacy pays	$0.12 /mL	$0.12 /mL
Type	RX	RX
Active ingredient	DOXYCYCLINE HYCLATE	DOXYCYCLINE
Manufacturer	Rachelle	Sun Pharm Inds Inc
Dosage forms	Injectable	Tablet
Drug class	Tetracycline-Class Drug	Tetracycline-Class Drug
Boxed warning	None	None
Half-life	about 16 to 22 hours in healthy adults	about 16 to 22 hours in healthy adults
Treats	Anthrax, Campylobacter Infections, Cholera	Anthrax, Campylobacter Infections, Cholera

doxychel hyclate xyrosa

Rating

New

Pharmacy pays

$0.12 /mL

Type

Active ingredient

DOXYCYCLINE HYCLATE

DOXYCYCLINE

Manufacturer

Rachelle

Sun Pharm Inds Inc

Dosage forms

Injectable

Tablet

Drug class

Tetracycline-Class Drug

Boxed warning

None

Half-life

about 16 to 22 hours in healthy adults

Treats

Anthrax, Campylobacter Infections, Cholera

Frequently asked questions

Which is cheaper, Doxychel Hyclate or Xyrosa?

Pharmacies pay about the same to acquire either one — roughly $0.12 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Doxychel Hyclate and Xyrosa?

Doxychel Hyclate contains Doxycycline Hyclate, while Xyrosa contains Doxycycline — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.