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DOXEPIN HYDROCHLORIDE vs SURMONTIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DOXEPIN HYDROCHLORIDE and SURMONTIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$4.84 /30

Type

RX
RX

Active ingredient

DOXEPIN HYDROCHLORIDE
TRIMIPRAMINE MALEATE

Dosage forms

Capsule, Topical, Solution, Tablet
Capsule

Drug class

Tricyclic Antidepressant
Tricyclic Antidepressant

Boxed warning

None
None

Half-life

about 8 to 24 hours (average about 17 hours)

Treats

Anxiety Disorders, Depressive Disorder, Atopic Dermatitis
Depressive Disorder

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Frequently asked questions

What is the difference between Doxepin Hydrochloride and Surmontil?

Doxepin Hydrochloride contains Doxepin Hydrochloride, while Surmontil contains Trimipramine Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.