DOXEPIN HYDROCHLORIDE vs JANIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DOXEPIN HYDROCHLORIDE and JANIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DOXEPIN HYDROCHLORIDE	JANIMINE
Rating	70/100	70/100
Pharmacy pays	~$4.84 /30	~$2.54 /30
Type	RX	RX
Active ingredient	DOXEPIN HYDROCHLORIDE	IMIPRAMINE HYDROCHLORIDE
Manufacturer	Watson Labs	Abbott
Dosage forms	Capsule, Topical, Solution, Tablet	Tablet
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Half-life	about 8 to 24 hours (average about 17 hours)	—
Treats	Anxiety Disorders, Depressive Disorder, Atopic Dermatitis	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

doxepin hydrochloride janimine

Rating

70/100

Pharmacy pays

~$4.84 /30

~$2.54 /30

Type

Active ingredient

DOXEPIN HYDROCHLORIDE

IMIPRAMINE HYDROCHLORIDE

Manufacturer

Watson Labs

Abbott

Dosage forms

Capsule, Topical, Solution, Tablet

Tablet

Drug class

Tricyclic Antidepressant

Boxed warning

None

Half-life

about 8 to 24 hours (average about 17 hours)

—

Treats

Anxiety Disorders, Depressive Disorder, Atopic Dermatitis

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

Which is better-rated, Doxepin Hydrochloride or Janimine?

Doxepin Hydrochloride and Janimine are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Doxepin Hydrochloride or Janimine?

Janimine costs pharmacies less to acquire — about $2.54 vs $4.84 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Doxepin Hydrochloride and Janimine?

Doxepin Hydrochloride contains Doxepin Hydrochloride, while Janimine contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.