DOSTINEX vs METHERGINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. DOSTINEX and METHERGINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DOSTINEX	METHERGINE
Rating	64/100	New
Pharmacy pays	~$42.43 /30	~$158.98 /30
Type	RX	RX
Active ingredient	CABERGOLINE	METHYLERGONOVINE MALEATE
Manufacturer	Pfizer	Edison Theraps LLC
Dosage forms	Tablet	Tablet
Drug class	Ergot Derivative	Ergot Derivative
Boxed warning	None	None
Half-life	—	a mean of about 3.4 hours (range 1.5 to 12.7 hours)
Treats	Adenoma, Hyperprolactinemia, Parkinson Disease	Postpartum Hemorrhage

dostinex methergine

Rating

64/100

New

Pharmacy pays

~$42.43 /30

~$158.98 /30

Type

Active ingredient

CABERGOLINE

METHYLERGONOVINE MALEATE

Manufacturer

Pfizer

Edison Theraps LLC

Dosage forms

Tablet

Drug class

Ergot Derivative

Boxed warning

None

Half-life

—

a mean of about 3.4 hours (range 1.5 to 12.7 hours)

Treats

Adenoma, Hyperprolactinemia, Parkinson Disease

Postpartum Hemorrhage

Frequently asked questions

Which is cheaper, Dostinex or Methergine?

Dostinex costs pharmacies less to acquire — about $42.43 vs $158.98 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dostinex and Methergine?

Dostinex contains Cabergoline, while Methergine contains Methylergonovine Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.