DOLOPHINE HYDROCHLORIDE vs QDOLO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DOLOPHINE HYDROCHLORIDE and QDOLO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DOLOPHINE HYDROCHLORIDE	QDOLO
Rating	72/100	New
Pharmacy pays	$0.18 /mL	~$0.72 /30
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE
Manufacturer	Hikma	Rosemont
Dosage forms	Tablet, Syrup	Solution
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	Boxed warning
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
Treats	Opioid-Related Disorders, Intractable Pain	Pain

dolophine hydrochloride qdolo

Rating

72/100

New

Pharmacy pays

$0.18 /mL

~$0.72 /30

Type

Active ingredient

METHADONE HYDROCHLORIDE

TRAMADOL HYDROCHLORIDE

Manufacturer

Hikma

Rosemont

Dosage forms

Tablet, Syrup

Solution

Drug class

Opioid Agonist

Boxed warning

None

Boxed warning

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Opioid-Related Disorders, Intractable Pain

Pain

Frequently asked questions

What is the difference between Dolophine Hydrochloride and Qdolo?

Dolophine Hydrochloride contains Methadone Hydrochloride, while Qdolo contains Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.