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DILTIAZEM HYDROCHLORIDE vs VERAPAMIL HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DILTIAZEM HYDROCHLORIDE and VERAPAMIL HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

diltiazem hydrochlorideverapamil hydrochloride

Rating

New
70/100

Pharmacy pays

~$9.18 /30
~$5.71 /30

Type

RX
RX

Active ingredient

DILTIAZEM HYDROCHLORIDE
VERAPAMIL HYDROCHLORIDE

Manufacturer

Nesher Pharms
Watson Labs

Dosage forms

Capsule, extended release, Injectable, Powder, Solution, Tablet, Tablet, extended release
Injectable, Tablet, Tablet, extended release

Drug class

Calcium Channel Blocker
Calcium Channel Blocker

Boxed warning

None
None

Half-life

about 3 to 4.5 hours
about 2.8 to 7.4 hours after a single dose, rising to about 4.5 to 12 hours with repeated dosing

Treats

Variant Angina Pectoris, Atrial Fibrillation, Atrial Flutter
Variant Angina Pectoris, Atrial Fibrillation, Atrial Flutter

Frequently asked questions

Which is cheaper, Diltiazem Hydrochloride or Verapamil Hydrochloride?

Verapamil Hydrochloride costs pharmacies less to acquire — about $5.71 vs $9.18 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diltiazem Hydrochloride and Verapamil Hydrochloride?

Diltiazem Hydrochloride contains Diltiazem Hydrochloride, while Verapamil Hydrochloride contains Verapamil Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.