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DILAUDID vs DURAMORPH PF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. DILAUDID and DURAMORPH PF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
70/100

Pharmacy pays

$0.57 /mL
$2.61 /mL

Type

RX
RX

Active ingredient

HYDROMORPHONE HYDROCHLORIDE
MORPHINE SULFATE

Dosage forms

Injectable, Solution, Tablet
Injectable, Solution

Drug class

Opioid Agonist
Opioid Agonist

Half-life

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid
about 2 hours

Treats

Cough, Postoperative Pain
Dyspnea, Intractable Pain

Frequently asked questions

Which is better-rated, Dilaudid or Duramorph Pf?

By our independent rating, Duramorph Pf scores higher — 3.5 vs 3.4 out of 5 for Dilaudid. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dilaudid or Duramorph Pf?

Dilaudid costs pharmacies less to acquire — about $0.57 vs $2.61 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dilaudid and Duramorph Pf?

Dilaudid contains Hydromorphone Hydrochloride, while Duramorph Pf contains Morphine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.