DILAUDID-HP vs WESTADONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DILAUDID-HP and WESTADONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DILAUDID-HP	WESTADONE
Rating	68/100	68/100
Pharmacy pays	$0.57 /mL	$0.18 /mL
Type	RX	RX
Active ingredient	HYDROMORPHONE HYDROCHLORIDE	METHADONE HYDROCHLORIDE
Manufacturer	Fresenius Kabi USA	Sandoz
Dosage forms	Injectable	Tablet, effervescent
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	None
Half-life	about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid	about 8 to 59 hours (terminal/elimination half-life; a very wide range)
Treats	Cough, Postoperative Pain	Opioid-Related Disorders, Intractable Pain

dilaudid-hp westadone

Rating

68/100

Pharmacy pays

$0.57 /mL

$0.18 /mL

Type

Active ingredient

HYDROMORPHONE HYDROCHLORIDE

METHADONE HYDROCHLORIDE

Manufacturer

Fresenius Kabi USA

Sandoz

Dosage forms

Injectable

Tablet, effervescent

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Cough, Postoperative Pain

Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is better-rated, Dilaudid-Hp or Westadone?

Dilaudid-Hp and Westadone are tied at 3.4 out of 5 by our independent rating.

Which is cheaper, Dilaudid-Hp or Westadone?

Westadone costs pharmacies less to acquire — about $0.18 vs $0.57 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dilaudid-Hp and Westadone?

Dilaudid-Hp contains Hydromorphone Hydrochloride, while Westadone contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.