DILAUDID-HP vs SUFENTA PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. DILAUDID-HP and SUFENTA PRESERVATIVE FREE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DILAUDID-HP	SUFENTA PRESERVATIVE FREE
Rating	68/100	72/100
Pharmacy pays	$0.57 /mL	—
Type	RX	RX
Active ingredient	HYDROMORPHONE HYDROCHLORIDE	SUFENTANIL CITRATE
Manufacturer	Fresenius Kabi USA	Rising
Dosage forms	Injectable	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	None
Half-life	about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid	—
Treats	Cough, Postoperative Pain	Pain

dilaudid-hp sufenta preservative free

Rating

68/100

72/100

Pharmacy pays

$0.57 /mL

—

Type

Active ingredient

HYDROMORPHONE HYDROCHLORIDE

SUFENTANIL CITRATE

Manufacturer

Fresenius Kabi USA

Rising

Dosage forms

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid

—

Treats

Cough, Postoperative Pain

Pain

Frequently asked questions

Which is better-rated, Dilaudid-Hp or Sufenta Preservative Free?

By our independent rating, Sufenta Preservative Free scores higher — 3.6 vs 3.4 out of 5 for Dilaudid-Hp. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Dilaudid-Hp and Sufenta Preservative Free?

Dilaudid-Hp contains Hydromorphone Hydrochloride, while Sufenta Preservative Free contains Sufentanil Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.