Skip to content
ppharmaranks
Menu

DIFLUCAN vs MYCELEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

60/100
New

Pharmacy pays

$0.42 /mL
$0.21 /mL

Type

RX
OTC

Active ingredient

FLUCONAZOLE
CLOTRIMAZOLE

Dosage forms

Powder
Lozenge, Solution, Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Half-life

about 30 hours (range 20 to 50 hours)

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis
Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis

Get diflucanhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

Frequently asked questions

Which is cheaper, Diflucan or Mycelex?

Mycelex costs pharmacies less to acquire — about $0.21 vs $0.42 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diflucan and Mycelex?

Diflucan contains Fluconazole, while Mycelex contains Clotrimazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.